Activity Number 299
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	Overview and Learning Objectives
	Activity Credits
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Drug Design: Protein Kinases

Interactive, scaffolded model

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	Overview and Learning Objectives Much effort has been put into understanding the structure and function of molecules, so that computers can be used to more quickly and efficiently aid in the design of drugs for many different diseases. In this activity we will explore what is known about one particular kind of molecule that is a target for new drugs - protein kinases. Students review protein structure and hydrophilic/phobic interactions, and then study kinases, small proteins that regulate numerous cell processes. Students will be able to • relate protein structure to its function • identify component structures and forces that maintain a protein's shape (hydrogen bonds, hydrophilic and hydrophobic interactions) • describe what a researcher would look for when they start to design a protein that could block a kinase. return to top



	Activity Credits Created by CC: Molecular Literacy return to top



	Requirements return to top

These materials are based upon work supported by the
National Science Foundation under grant number DUE-0402553

Any opinions, findings, and conclusions
or recommendations expressed in this material are those of
the author(s) and do not necessarily reflect the views
of the National Science Foundation.

Drug Design: Protein Kinases

Overview and Learning Objectives

Activity Credits

Requirements