Activity Number 76

	Overview and Learning Objectives
	Assessment
	Central Concepts
	Textbook References
	Activity Credits
	Requirements

How a Protein Gets Its Shape: The Role of Charge

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	Overview and Learning Objectives Students will be able to: Discuss the role of charged areas of molecules in folding polymer chains into specific shapes. Reason about the forces that bring polymers together into complex cellular structures. Give several examples of cellular machinery and compare them to macroscopic tools and machines. return to top



	Assessment See question 1 from the following pre/post- test: http://www.concord.org/~barbara/workbench_web/unitV/prepost_test.html return to top



	Central Concepts Key Concept: Monomers with different charges attract each other; those with identical charges repel each other. The interactions among charged monomers within the polymer help determine the polymer shape. Additional Related Concepts Biology Sickle Cell Anemia Molecular Biology Amino acid Protein Protein Folding Self-assembly Physics/Chemistry Charge return to top



	Textbook References Biology (Miller and Levine) Prentice Hall 5th Edition - Unit 2: Chapter 7 - Nucleic Acids and Protein Synthesis Biology: Exploring Life - Chapter 5: The Molecules of Life BSCS Blue (8th Edition) - Chapter 9: Expressing Genetic Information Web of Life - Chapter 8: Protein Synthesis return to top



	Activity Credits Created by CC Project: Molecular Workbench using Molecular Workbench return to top



	Requirements Java 1.5+ - Java 1.5+ is available for Windows, Linux, and Mac OS X 10.4 and greater. If you are using Mac OS X 10.3, you can download MW Version 1.3 and explore within it instead. return to top

These materials are based upon work supported by the
National Science Foundation under grant number DUE-0402553

Any opinions, findings, and conclusions
or recommendations expressed in this material are those of
the author(s) and do not necessarily reflect the views
of the National Science Foundation.

How a Protein Gets Its Shape: The Role of Charge

Overview and Learning Objectives

Assessment

Central Concepts

Additional Related Concepts

Textbook References

Activity Credits

Requirements